Physical contact, excitement of sexual arousal, thrusts of sexual intercourse followed by orgasm all are the sources of sexual satisfaction. Unfortunately the victims of impotence are unable to enjoy the pleasures of sexual relation fully because of the inability to erect the penis. Sexual relationship gets threatened by the disease of impotence. Although a number of pharmaceutical companies endeavored to synthesize drugs for the treatment of this disease but the most effective drug manufactured till the date is Viagra developed by Pfizer, a competent pharmaceutical company, in 1998. Viagra has gained enormous popularity since its introduction in the market because of its high efficiency and its effectiveness to treat impotence in men of any age group.
Role of Viagra in Achieving Erection
The fascinating mechanism of erection starts when you are sexually aroused. As soon as the brain senses sexual stimulation being provided to the body, it starts sending signals to the penis. Signals from the brain reaching the penis stimulates the dilatation of the vessels of the penis. The dilatation of the penile vessels allows more and more blood to enter in the sinuses of the spongy tissue, called carpus cavarnosa, of the penis. Blood filling the sinuses is not allowed to leave because of the constriction of the veins of the penis. The trapped blood filling the sinuses of carpus cavarnosa is responsible for the erection of the penis. In impotence, although the signals are sent from the brain to the penis to dilate its vessels but the penile vessels are unable to dilate because of the deficiency of cGMP, a factor which brings about dilation. Viagra performs its amazing erectile action by compensating the deficiency of cGMP through its inhibitory effect on phoshpdiesterase, an enzyme which breaks down cGMP.
Physician's top recommendations:
The world most recommended impotence treatment is available in 25 mg, 50 mg and 100 mg tablets that are typically diamond shaped and blue colored. One of these pills, 25 mg for starters, is to be taken with glassful of water 30 minutes before sexual interaction. The drug is expected to accelerate your erection for four hours when accompanied by appropriate sexual stimulation. Increase in milli-gram dosage might be followed after realizing that the previously administered Viagra dose is not eliciting sufficient response. In case you have been suffering from liver disease in the past, do not take the drug unless recommended by the physician because liver is the primary drug metabolizing centre of the body. The drugs which are rendered incompatible with Viagra are nitrate containing cardiac treatments, protease inhibitors and erythromycin antibiotics. Reinforced action of nitrates might produce life threatening hypotension so is strongly contraindicated.
Why the side effects?
Tissues of eyes, ears and other body organs are also stimulated by Viagra apart from PDE5 which it targets primarily, thereby producing side effects on account of the former causes. Some of the prominent side effects are cyanotic visual reception, decreased power to listen, dizziness, hypotension, diarrhea, nasal congestion and runny nose. If they persist, contact your physician without delay.
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